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The peptide's activation of ERK1/2 and downstream transcription factors including Egr-1 drives expression of collagen synthesis genes while its enhancement of cellular migration ensures efficient fibroblast recruitment to sites requiring matrix deposition, creating optimal conditions for rapid yet organized tissue reconstruction

Financial support and sponsorship This work was supported by Fondo de Investigacin Sanitaria-FEDER (PI25/00528) and CIBEROBN from the Spanish Instituto de Salud Carlos III, and the Department of Health of the Gobierno de Navarra (GN2025/52)